Objective: To analyze the psychological factors associated with family functionality in pregnant women with pregestational and gestational diabetes.

Materials and Methods: Observational, prospective, cross-sectional, and comparative study conducted at a Family Medicine Unit in Veracruz, Mexico, between October 2024 and February 2025. A total of 135 pregnant women were included, both with and without diabetes, and normoevolutive. The FF-SIL test was used to assess family functionality, and the HADS scale was applied to evaluate psychological factors such as anxiety and depression. Descriptive statistics and chi-square tests were used to analyze associations, with significance set at p<0.05.

Results: Regarding family functionality, among women with pregestational diabetes, 23 (51.11%) were functional, and 17 (37.78%) were moderately functional; among those with gestational diabetes, 27 (60%) were functional, and 15 (33.33%) were moderately functional; among normoevolutive women, 33 (73.3%) were functional, and 11 (24.4%) were moderately functional.

Regarding psychological factors, among those with pregestational diabetes, 17 (37.78%) presented anxiety, 6 (13.33%) presented both anxiety and depression, and 21 (46.67%) presented neither; among those with gestational diabetes, 16 (35.56%) had anxiety, and 19 (42.22%) had none; among normoevolutive women, 19 (42.22%) had anxiety, and 18 (40%) had none of these conditions.

An association was found between psychological factors and family functionality in pregnant women with pregestational diabetes (p = 0.0062), as well as in normoevolutive pregnant women (p = 0.0268).