Background and aim: Skin problems are commonly developed in chronic kidney disease. Our study aimed to assess and compare dermatological appearances in patients with chronic kidney disease (CKD) and end-stage renal disease at distinctive stages, non-dialysis patients, and hemodialysis patients.

Methodology: We conducted the study in the Department of Nephrology and Department of Dermatology and Venereology of Dhaka Medical College Hospital. Dhaka. The time period was January 2019 to June 2019. The study design was descriptive cross-sectional. All patients who were diagnosed at different stages of CKD irrespective of the requirement of dialysis or not were enrolled in the study by purposive sampling from the Department of Nephrology and the Department of Dermatology and Venereology of Dhaka Medical College Hospital, Dhaka. Thereafter, they were scrutinized according to eligibility criteria and 60 patients were finalized. A pre-tested, observation-based, peer-reviewed data collection sheet was prepared before the study. Data regarding clinical biochemical and surgical profiles were recorded. Data were compiled, edited, and analyzed.

Results: The mean age of the undialysed patients and dialyzed patients were 46.73±8.79 years (age range: 18 - 60 years) and 54.79±6.27 years (range: 21 - 59 years) respectively. Among 50 undialysed patients, 32(64%) were male and 18(36%) were female. On the contrary. among 50 dialyzed patients 38(76% were male and 12(24%) were female. Out of 50 dialyzed patients, the highest 18(36%) had the duration of disease for 25-36 months. Out of 50 undialysed patients 36(72%), 12(24%), and 2(4%) had CKD stage 3, 4, and 5 respectively whereas all the dialysed patients were diagnosed an ESRD or stage 5 disease. Out of 50 undialysed patients, the highest 27(54%) had pruritus which was subsequently followed by 16(32%) Xerosis manifestation.