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VOL. 3, ISSUE 3 (2021)
An update on serrated lesions of large intestine
Authors
Aarti Dhatwalia, Vineet Kumar, Vandana Raghuvanshi, Varun Jaswal
Abstract
Approximately 25% of sporadic colorectal cancers (CRCs) arise via serrated precursor lesions. Both colonoscopy and/or stool-based tests are utilized for surveillance but only colonoscopy allows for resection of precursor lesions. Serrated polyp is an umbrella term that encompasses HPs, sessile serrated lesions (SSLs), and traditional serrated adenomas (TSAs). In most serrated polyps, the first step of the pathway is believed to be acquisition of a mutation in a gene that regulates mitogen-activated protein kinase pathway. This review summarizes precursor lesions of colorectal adenocarcinoma arising along the “serrated pathway.”
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Pages:24-26
How to cite this article:
Aarti Dhatwalia, Vineet Kumar, Vandana Raghuvanshi, Varun Jaswal "An update on serrated lesions of large intestine ". International Journal of Medical Science and Clinical Research, Vol 3, Issue 3, 2021, Pages 24-26
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