Prenatally diagnosed Trisomy 16 mosaicism is related with variable pregnancy outcomes accepted from stillbirth with multiple congenital abnormalities and it is common as well in mosaic trisomy 16, huge level of trisomy 16 is mismatched with postnatal existence with maximum trisomy 16 conceptions impulsively aborting within the gestation period of 8 to 15 weeks. It is still unclear whether the level of trisomy in dissimilar fetal-placental tissues is an interpreter of pregnancy outcome or not. Cytogenetic analysis was carried out with blood lymphocytes and the metaphases witnessed with mosaic trisomy of chromosome.