International Journal of Medical Science and Clinical Research

International Journal of Medical Science and Clinical Research


International Journal of Medical Science and Clinical Research
International Journal of Medical Science and Clinical Research
2019, Vol. 1, Issue 1
Urinary Tract Infections: Culture and Sensitivity Patterns: A Two Year Experience At A Peripheral Hospital

Dr. Gurmeet Singh Sarla

Background: Most of the urinary tract infections are treated with empirical antibiotics resulting in increased antibiotic resistance due to indiscriminate and improper use of antimicrobial agents. Objective: This study was designed to find out the causative microbial agents of UTI and determine the antimicrobial susceptibility and resistance pattern of the bacterial pathogens isolated from urine culture to act as a guide for choosing the correct antibiotic in these patients thereby reducing antibiotic resistance and treating UTI with culture specific antibiotics rather than using a random, empirically selected antibiotic. Materials and Methods: In this study, 112 urine specimens out of 300 which showed growth of micro-organisms on culture and sensitivity studies were analysed for antibiotic susceptibility pattern. The susceptibility of microbes to Co-trimoxazole, Amikacin, Gentamycin, Ceftriaxone, Ceftazidime, Cefixime, Cefuroxime, Norfloxacin, Ciprofloxacin, Ofloxacin, Co-amoxyclav, Levofloxacin, Linezolid and Nitrofurantoin were tested with disc diffusion agar test. Results: 112 (37.33%) urine specimens out of 300 showed growth of micro-organisms on culture and sensitivity studies. The most common age group affected of the positive urine culture test report was 31-40 years which affected 36 patients out of 112 patients (32.14%). Females were more commonly affected as compared to males (62 female patients: 55.35% as compared to 50 male Patients: 44.64%). E Coli was the most common causative organism as revealed by urine culture tests (104 patients: 92.85%). 88.39% of the isolates were susceptible to Amikacin followed closely by Nitrofurantoin to which 77.67% of microbes were found to be sensitive. Highest antibiotic resistance of 49.10% was seen with Co- amoxyclav. Conclusion: Use of culture specific antimicrobial agents is recommended which will reduce antibiotic resistance. As per our study, injectable Amikacin and oral Nitrofurantoin have been found to be most effective in the treatment of urinary tract infections
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How to cite this article:
Dr. Gurmeet Singh Sarla. Urinary Tract Infections: Culture and Sensitivity Patterns: A Two Year Experience At A Peripheral Hospital. International Journal of Medical Science and Clinical Research. 2019; 1(1): 21-24.